Autopsies counsel COVID’s odor loss is brought on by irritation, not virus

A woman holds a nasal swab for a COVID-19 antigen rapid test in front of her desk on January 5 in Berlin.

Enlarge / A girl holds a nasal swab for a COVID-19 antigen speedy take a look at in entrance of her desk on January 5 in Berlin. (credit score: Getty | Thomas Trutschel)

Though the lack of odor and style grew to become obvious signs of COVID-19 early within the pandemic, researchers are nonetheless figuring out why that occurs—is the virus immediately infecting and destroying the cells chargeable for these essential senses, or is it collateral harm from our immune techniques combating off the invading foe?

In keeping with a postmortem examine out this week in JAMA Neurology, it is the latter. The examine—which dove deep into the noses, nerves, and brains of 23 individuals who died of COVID-19—is probably the most detailed have a look at the coronavirus’ results on our sniffers. Researchers concluded that irritation—not the virus—is behind the lack of odor and style throughout a bout of COVID-19, which is sweet information in some methods. It means that remedies with anti-inflammatory medicine might stop extreme or long-term harm to these essential senses.

The discovering follows a mixture of knowledge on the consequences of SARS-CoV-2 on our sense of odor. Some knowledge recommended that the virus can infect the nerves that carry smells alerts to our mind—olfactory neurons. Thus, the misplaced senses might be brought on by direct infections. However others discovered that the virus wasn’t current in these neurons at demise.

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